What is the Zephyr® Valve:

The Zephyr Valve is the most studied minimally-invasive endobronchial device for emphysema and has consistently been shown to be a safe and effective treatment for patients with severe emphysema.1

Patients treated with Zephyr Valves have shown significant clinical and statistical improvements in lung function, exercise capacity, and quality of life compared to medical management alone.

Who is the Zephyr^® Valve for?

Severe emphysema patients who consistently feel short of breath despite using COPD medications and/or oxygen.

How does the Procedure Work?

The one-time procedure is done during a bronchoscopy that requires no cutting or incisions. During the procedure, on average 4 tiny valves are placed in the airways to block off the diseased parts of the lungs. The valves reduce hyperinflation, preventing air from being trapped in the diseased area of the lung and allowing healthier parts of the lung to take in more air. This results in patients being able to breathe easier. Patients treated have reported immediate relief.

What can Patients Expect?

A typical Zephyr^® valve procedure looks like this:

• The doctor will give you medicine to make you sleepy.
• A small tube with a camera, called a bronchoscope, will be inserted into your lungs through your nose or mouth.
• During the procedure on average the doctor will place 4 Zephyr Valves in the airways.
• You will stay in the hospital for approximately 3 nights for observation.
• After the procedure, you will continue to use the medicines that your doctor has prescribed for your condition.

Complications of the Zephyr Endobronchial Valve treatment can include but are not limited to pneumothorax, worsening of COPD symptoms, hemoptysis, pneumonia, dyspnea and, in rare cases, death.

¹ Criner G et al AM J Resp Crit Care Med 2018, Published on 22-May-2018 as 10.1164/rccm.201803-0590OC